Jet-lagged mice die young, U.S. study finds

I read this today, and just could not fucking believe it. How could that be sensibly explained? Scientists nowadays are jolting the living shit out of people with some of their uncanny theories. The probably get together and come up with some bizarre things to do among themselves, like “hey, let’s screw up some poor mice life routine by putting this poor animal in all sort of tests and poke them with all kinda of chemicals and come up with some creepy theory that shit-scare people out there,..heck.. we are scientists, they’ll believe us!”

I am nearing 40 years of age, damn….. time does fucking fly. 40 is a ‘magic’ number, bet you’ve heard that before. It triggers us for many reasons, literally the number..well it doesn’t sound like you are young (when my father was 40, I thought he was old already..), and religiously 40 was a major milestone in our prophet life. Personally, though I may think I am the same person 20 years ago, I might have changed in many aspects of my life over these years. If 20 years ago, I could just sing ‘dunia-ini-hanya-sementara’ without a friction of feel on what it actually means, but now I think I’d rather not to sing it. Not to mention that I am sounding more and more like my parents now. Actually it is just that our life priority evolves over, and most apparent we are very much becoming family-focused now, putting so much effort for our children well-being, so they’ll be good Muslims and not turn into some scumbags that can bring the whole civilization down in the future.

WASHINGTON (Reuters) – Jet-lagged mice die younger, researchers said on Monday in a study that suggests that working unusual shifts and flying back and forth across time zones takes a permanent toll on health.  Tests on more than 100 mice showed that old mice forced to live on a confusing schedules of light and darkness, simulating rotating shifts or international travel, died sooner than those on gentler schedules.  Young mice treated in a similar way did just fine, the researchers at the University of Virginia added in a report published in the journal Current Biology.  Gene Block, a professor of biology, and colleague Alec Davidson said they stumbled onto the findings by accident.  Genetically engineered mice in another experiment died when they were put under lights six hours earlier than usual, but no mice died if the light schedule was delayed.  So they tested three groups of mice, with about 30 old mice and 9 young mice in each group.  One group had its light/dark cycle shifted forward by six hours — the equivalent of waking people up six hours early — every week for eight weeks.  A second group had its schedule shifted back by six hours, and the third group’s schedule was unaltered.  They found that 83 percent of old mice survived under the normal schedule, 68 percent lived after eight weeks of shifting steadily backward, but fewer than half — 47 percent — survived when the lights regularly came on six hours earlier.  When they speeded the schedule up, changing the light schedule every four days, even more mice died.  The mice were not obviously stressed by this — their daily levels of a stress hormone called corticosterone did not increase.  “Alternatively, the general frailty of older animals rather than age-related changes in the circadian system may make them less able to tolerate changes in the light schedule,” the researchers wrote. Other studies have shown that hormones associated with wake/sleep cycles, such as melatonin, as well as so-called “clock” genes, can affect aging and immune system processes.  Copyright © 2006 Reuters

~ by pickholes on November 7, 2006.

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